BDBM50203383 CHEMBL228972::N-(1-benzylpiperidin-4-yl)-2-naphthamide::N-(1-benzylpiperidine-4-yl)-2-naphthamide

SMILES O=C(NC1CCN(Cc2ccccc2)CC1)c1ccc2ccccc2c1

InChI Key InChIKey=RQEOFDOXFRRFQL-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50203383   

TargetD(4) dopamine receptor(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50203383(N-(1-benzylpiperidine-4-yl)-2-naphthamide | N-(1-b...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]nemonapride from human cloned dopamine D4.2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50203383(N-(1-benzylpiperidine-4-yl)-2-naphthamide | N-(1-b...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]nemonapride from human cloned dopamine D4.2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50203383(N-(1-benzylpiperidine-4-yl)-2-naphthamide | N-(1-b...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]ketanserin from rat 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50203383(N-(1-benzylpiperidine-4-yl)-2-naphthamide | N-(1-b...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]ketanserin from rat cloned 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50203383(N-(1-benzylpiperidine-4-yl)-2-naphthamide | N-(1-b...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50203383(N-(1-benzylpiperidine-4-yl)-2-naphthamide | N-(1-b...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50203383(N-(1-benzylpiperidine-4-yl)-2-naphthamide | N-(1-b...)
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of human BGT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50203383(N-(1-benzylpiperidine-4-yl)-2-naphthamide | N-(1-b...)
Affinity DataKi:  2.30E+4nMAssay Description:Inhibition of human GAT2 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50203383(N-(1-benzylpiperidine-4-yl)-2-naphthamide | N-(1-b...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human GAT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50203383(N-(1-benzylpiperidine-4-yl)-2-naphthamide | N-(1-b...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human GAT3 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed