BDBM50203362 (3S)-3-(2-(5-tert-butyl-3-(1-carboxy-3-methylbutylamino)-2-oxopyrazin-1(2H)-yl)butanamido)-4-oxo-7-phenylheptanoic acid::CHEMBL396625

SMILES CCC(C(=O)N[C@@H](CC(O)=O)C(=O)CCCc1ccccc1)n1cc(nc(NC(CC(C)C)C(O)=O)c1=O)C(C)(C)C

InChI Key InChIKey=VHRFTKXADAZJCT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50203362   

TargetCaspase-7(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50203362((3S)-3-(2-(5-tert-butyl-3-(1-carboxy-3-methylbutyl...)
Affinity DataIC50: 3.49E+3nMAssay Description:Inhibition of human recombinant caspase 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50203362((3S)-3-(2-(5-tert-butyl-3-(1-carboxy-3-methylbutyl...)
Affinity DataIC50: 5.49E+3nMAssay Description:Inhibition of human recombinant caspase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50203362((3S)-3-(2-(5-tert-butyl-3-(1-carboxy-3-methylbutyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant caspase 8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50203362((3S)-3-(2-(5-tert-butyl-3-(1-carboxy-3-methylbutyl...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant caspase 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed