BDBM50203203 (S)-3-(naphthalene-7-sulfonamido)-3-phenyl-N-((R)-7-(piperidin-1-ylmethyl)chroman-4-yl)propanamide::CHEMBL415849

SMILES O=C(C[C@H](NS(=O)(=O)c1ccc2ccccc2c1)c1ccccc1)N[C@@H]1CCOc2cc(CN3CCCCC3)ccc12

InChI Key InChIKey=IQPWKAIEQBOLPJ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50203203   

TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50203203((S)-3-(naphthalene-7-sulfonamido)-3-phenyl-N-((R)-...)
Affinity DataIC50: 519nMAssay Description:Antagonistic activity at human bradykinin B1 receptor expressed in CHO cells assessed as effect on DAK-mediated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50203203((S)-3-(naphthalene-7-sulfonamido)-3-phenyl-N-((R)-...)
Affinity DataKi:  143nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHO-D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed