BDBM50202947 (+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-fluorophenyl)-2-(4-isopropylpiperazin-1-yl)ethyl]piperazine::CHEMBL226176

SMILES CC(C)N1CCN(CC1)C(CN1CCN(CCCc2c(F)cccc2-c2ccccc2)CC1)c1ccc(F)cc1

InChI Key InChIKey=PAVIGVDFHAXYTL-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50202947   

TargetHistamine H1 receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50202947((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]pyrilamine from histamine H1 receptor in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50202947((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]DAMGO from mu opiate receptor in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50202947((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 1.46E+3nMAssay Description:Displacement of [3H]paroxatine from SET in rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50202947((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 206nMAssay Description:Displacement of [3H]nisoxetine from NET in rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50202947((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]DPDPE from delta opiate receptor in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50202947((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]raclopride from dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50202947((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 11.7nMAssay Description:Displacement of [125I]Nle4-D-Phe7-alpha-MSH from human MC4 receptor expressed in COS1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed