BDBM50202735 CHEMBL395666::N-(4-(4-amino-7-(3-((1s,4s)-4-aminocyclohexylamino)prop-1-enyl)thieno[3,2-c]pyridin-3-yl)-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide

SMILES COc1cc(ccc1NC(=O)c1cc2ccccc2n1C)-c1csc2c(\C=C\CN[C@@H]3CC[C@H](N)CC3)cnc(N)c12

InChI Key InChIKey=FRQGIFZNGIECRT-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50202735   

TargetAngiopoietin-1 receptor(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202735(N-(4-(4-amino-7-(3-((1s,4s)-4-aminocyclohexylamino...)
Affinity DataIC50: 570nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202735(N-(4-(4-amino-7-(3-((1s,4s)-4-aminocyclohexylamino...)
Affinity DataIC50: 480nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202735(N-(4-(4-amino-7-(3-((1s,4s)-4-aminocyclohexylamino...)
Affinity DataIC50: 2.71E+4nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fgr(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202735(N-(4-(4-amino-7-(3-((1s,4s)-4-aminocyclohexylamino...)
Affinity DataIC50: 2.17E+4nMAssay Description:Inhibition of FgrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202735(N-(4-(4-amino-7-(3-((1s,4s)-4-aminocyclohexylamino...)
Affinity DataIC50: 2.63E+4nMAssay Description:Inhibition of FynMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202735(N-(4-(4-amino-7-(3-((1s,4s)-4-aminocyclohexylamino...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202735(N-(4-(4-amino-7-(3-((1s,4s)-4-aminocyclohexylamino...)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202735(N-(4-(4-amino-7-(3-((1s,4s)-4-aminocyclohexylamino...)
Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of HckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed