BDBM50202734 CHEMBL232542::N-(4-(4-amino-7-(3-(diethylamino)prop-1-enyl)thieno[3,2-c]pyridin-3-yl)-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide

SMILES CCN(CC)C\C=C\c1cnc(N)c2c(csc12)-c1ccc(NC(=O)c2cc3ccccc3n2C)c(OC)c1

InChI Key InChIKey=HFNVVIKLQRUGQK-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50202734   

TargetTyrosine-protein kinase Fgr(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202734(N-(4-(4-amino-7-(3-(diethylamino)prop-1-enyl)thien...)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of FgrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202734(N-(4-(4-amino-7-(3-(diethylamino)prop-1-enyl)thien...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202734(N-(4-(4-amino-7-(3-(diethylamino)prop-1-enyl)thien...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202734(N-(4-(4-amino-7-(3-(diethylamino)prop-1-enyl)thien...)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202734(N-(4-(4-amino-7-(3-(diethylamino)prop-1-enyl)thien...)
Affinity DataIC50: 9.05E+3nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202734(N-(4-(4-amino-7-(3-(diethylamino)prop-1-enyl)thien...)
Affinity DataIC50: 4.41E+4nMAssay Description:Inhibition of FynMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202734(N-(4-(4-amino-7-(3-(diethylamino)prop-1-enyl)thien...)
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibition of HckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202734(N-(4-(4-amino-7-(3-(diethylamino)prop-1-enyl)thien...)
Affinity DataIC50: 290nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed