BDBM50202417 CHEMBL219164::methyl 4'-{[({1-[(2,2-dichloropropanoyl)amino]cyclopropyl}-carbonyl)amino]methyl}-3,3'-difluoro-1,1'-biphenyl-2-carboxylate

SMILES COC(=O)c1c(F)cccc1-c1ccc(CNC(=O)C2(CC2)NC(=O)C(C)(Cl)Cl)c(F)c1

InChI Key InChIKey=HVTMHVBWOSYYLY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50202417   

TargetB2 bradykinin receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202417(methyl 4'-{[({1-[(2,2-dichloropropanoyl)amino]cycl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human bradykinin B2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202417(methyl 4'-{[({1-[(2,2-dichloropropanoyl)amino]cycl...)
Affinity DataKi:  119nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed