BDBM50202414 CHEMBL218553::ethyl 3-chloro-3'-fluoro-4'-{(1R)-1-[({1-[(trifluoroacetyl)amino]cyclopropyl}carbonyl)amino]ethyl}-1,1'-biphenyl-2-carboxylate

SMILES CCOC(=O)c1c(Cl)cccc1-c1ccc([C@@H](C)NC(=O)C2(CC2)NC(=O)C(F)(F)F)c(F)c1

InChI Key InChIKey=JEVUFRSXVGVJII-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50202414   

TargetB1 bradykinin receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202414(ethyl 3-chloro-3'-fluoro-4'-{(1R)-1-[({1-[(trifluo...)
Affinity DataIC50: 9.10nMAssay Description:Activity at human bradykinin B1 receptor assessed as inhibition of Des-arg kallidin-induced increase of cytosolic calcium in CHO cells by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202414(ethyl 3-chloro-3'-fluoro-4'-{(1R)-1-[({1-[(trifluo...)
Affinity DataKi:  1.35nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed