BDBM50202298 (R)-7-Methyl-1,6,6a,7,8,9-hexahydro-1,7-diaza-benzo[cd]pyren-2-one::CHEMBL253318

SMILES CN1CCc2ccc3[nH]c(=O)c4cccc5C[C@@H]1c2c3c45

InChI Key InChIKey=GTFWUPYRBYXCRC-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50202298   

TargetSodium-dependent serotonin transporter(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50202298((R)-7-Methyl-1,6,6a,7,8,9-hexahydro-1,7-diaza-benz...)
Affinity DataKi:  55nMAssay Description:Displacement of [3H]5-HT from rat SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50202298((R)-7-Methyl-1,6,6a,7,8,9-hexahydro-1,7-diaza-benz...)
Affinity DataKi:  55nMAssay Description:Binding affinity at 5HT7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50202298((R)-7-Methyl-1,6,6a,7,8,9-hexahydro-1,7-diaza-benz...)
Affinity DataKi:  55nMAssay Description:Displacement of [3H]raclopride from rat dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50202298((R)-7-Methyl-1,6,6a,7,8,9-hexahydro-1,7-diaza-benz...)
Affinity DataKi:  180nMAssay Description:Displacement of [3H]8-OH-DPAT from rat 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50202298((R)-7-Methyl-1,6,6a,7,8,9-hexahydro-1,7-diaza-benz...)
Affinity DataKi:  341nMAssay Description:In vitro binding affinity towards cloned rat 5-hydroxytryptamine 7 receptor using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50202298((R)-7-Methyl-1,6,6a,7,8,9-hexahydro-1,7-diaza-benz...)
Affinity DataKi:  373nMAssay Description:In vitro binding affinity towards cloned human 5-hydroxytryptamine 1A receptor expressed in Chinese hamster ovary (CHO) cells using [3H]8-OH-DPAT as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50202298((R)-7-Methyl-1,6,6a,7,8,9-hexahydro-1,7-diaza-benz...)
Affinity DataKi:  6.11E+3nMAssay Description:In vitro binding affinity towards cloned human Dopamine receptor D2A using [3H]- Raclopride as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed