BDBM50202246 CHEMBL3946224

SMILES COc1ccc2[nH]cc(CCNC(=O)c3cc(=O)c4c(OCc5ccccc5Br)cccc4o3)c2c1

InChI Key InChIKey=LVSWWEAJDCONJW-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50202246   

LigandPNGBDBM50202246(CHEMBL3946224)
Affinity DataEC50:  86nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in HEK293 cells assessed as reduction in mitoxantrone efflux after 30 mins by flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2018
Entry Details Article
PubMed
LigandPNGBDBM50202246(CHEMBL3946224)
Affinity DataEC50:  8.59E+7nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in HEK293 cells assessed as increase in mitoxantrone accumulation incubated for 30 mins by flow cytome...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
LigandPNGBDBM50202246(CHEMBL3946224)
Affinity DataEC50:  8.59E+7nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in HEK293 cells assessed as increase in mitoxantrone accumulation incubated for 30 mins by flow cytome...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed