BDBM50202146 5-(4-(benzyloxy)-3-methoxybenzylidene)-2-thioxothiazolidin-4-one::CHEMBL230515

SMILES COc1cc(C=C2SC(S)=NC2=O)ccc1OCc1ccccc1

InChI Key InChIKey=PNLIGOAITMKOBJ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50202146   

LigandPNGBDBM50202146(5-(4-(benzyloxy)-3-methoxybenzylidene)-2-thioxothi...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCDGSH iron-sulfur domain-containing protein 1(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM50202146(5-(4-(benzyloxy)-3-methoxybenzylidene)-2-thioxothi...)
Affinity DataIC50: 770nMAssay Description:Displacement of [3H]rosiglitazone from recombinant human C-terminal His-tagged MitoNEET cytosolic domain (32 to 108 residues) expressed in Escherichi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2018
Entry Details Article
PubMed
TargetCDGSH iron-sulfur domain-containing protein 1(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM50202146(5-(4-(benzyloxy)-3-methoxybenzylidene)-2-thioxothi...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]rosiglitazone from recombinant human C-terminal His-tagged MitoNEET cytosolic domain (32 to 108 residues) expressed in Escherichi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2018
Entry Details Article
PubMed