BDBM50202131 CHEMBL248356::N-(4-chloro-2-((1,3-dioxoisoindolin-2-yl)methyl)phenyl)-2-(trifluoromethyl)benzamide

SMILES FC(F)(F)c1ccccc1C(=O)Nc1ccc(Cl)cc1CN1C(=O)c2ccccc2C1=O

InChI Key InChIKey=KSNLPRQYWBIDPD-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50202131   

TargetMetabotropic glutamate receptor 5(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50202131(N-(4-chloro-2-((1,3-dioxoisoindolin-2-yl)methyl)ph...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202131(N-(4-chloro-2-((1,3-dioxoisoindolin-2-yl)methyl)ph...)
Affinity DataEC50:  5.70E+3nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed