BDBM50202096 CHEMBL219494::N-(5-fluoro-7-hydroxyadamantan-2-yl)-2-[4-(5-trifluoromethylpyridin-2-yl)piperazin-1-yl]propionamide

SMILES CC(N1CCN(CC1)c1ccc(cn1)C(F)(F)F)C(=O)N[C@H]1C2C[C@]3(O)CC1C[C@](F)(C2)C3

InChI Key

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50202096   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202096(N-(5-fluoro-7-hydroxyadamantan-2-yl)-2-[4-(5-trifl...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells by FPIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202096(N-(5-fluoro-7-hydroxyadamantan-2-yl)-2-[4-(5-trifl...)
Affinity DataKi:  46nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202096(N-(5-fluoro-7-hydroxyadamantan-2-yl)-2-[4-(5-trifl...)
Affinity DataKi:  910nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed