BDBM50202095 CHEMBL415429::E-(2R)-(3R-fluoro-pyrrolidin-1-yl)-N-(5-hydroxy-adamantan-2-yl)-propionamide

SMILES C[C@@H](N1CC[C@@H](F)C1)C(=O)N[C@H]1C2CC3CC1C[C@](O)(C3)C2

InChI Key

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50202095   

Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202095(E-(2R)-(3R-fluoro-pyrrolidin-1-yl)-N-(5-hydroxy-ad...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against mouse 11beta-HSD2 by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202095(E-(2R)-(3R-fluoro-pyrrolidin-1-yl)-N-(5-hydroxy-ad...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells by FPIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202095(E-(2R)-(3R-fluoro-pyrrolidin-1-yl)-N-(5-hydroxy-ad...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against human 11beta-HSD2 by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202095(E-(2R)-(3R-fluoro-pyrrolidin-1-yl)-N-(5-hydroxy-ad...)
Affinity DataKi:  9nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202095(E-(2R)-(3R-fluoro-pyrrolidin-1-yl)-N-(5-hydroxy-ad...)
Affinity DataKi:  12nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed