BDBM50202090 CHEMBL219443::N-(7-hydroxy-5-methoxy-adamantan-2-yl)-2-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-isobutyramide

SMILES CO[C@]12CC3C[C@](O)(CC(C1)C3NC(=O)C(C)(C)N1CCN(CC1)c1ccc(cn1)C(F)(F)F)C2

InChI Key

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50202090   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202090(N-(7-hydroxy-5-methoxy-adamantan-2-yl)-2-[4-(5-tri...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells by FPIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202090(N-(7-hydroxy-5-methoxy-adamantan-2-yl)-2-[4-(5-tri...)
Affinity DataKi:  6nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202090(N-(7-hydroxy-5-methoxy-adamantan-2-yl)-2-[4-(5-tri...)
Affinity DataKi:  180nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed