BDBM50202088 CHEMBL218142::N-adamantan-2-yl-2-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-acetamide

SMILES FC(F)(F)c1ccc(nc1)N1CCN(CC(=O)NC2C3CC4CC(C3)CC2C4)CC1

InChI Key

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50202088   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202088(N-adamantan-2-yl-2-[4-(5-trifluoromethyl-pyridin-2...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells by FPIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202088(N-adamantan-2-yl-2-[4-(5-trifluoromethyl-pyridin-2...)
Affinity DataKi:  24nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202088(N-adamantan-2-yl-2-[4-(5-trifluoromethyl-pyridin-2...)
Affinity DataKi:  51nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed