BDBM50201927 3-hydroxy-2-phenylquinoline-4-carboxylic acid::CHEMBL219376

SMILES OC(=O)c1c(O)c(nc2ccccc12)-c1ccccc1

InChI Key InChIKey=XAPRFLSJBSXESP-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50201927   

TargetP-selectin(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201927(3-hydroxy-2-phenylquinoline-4-carboxylic acid | CH...)
Affinity DataIC50: 6.50E+6nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50201927(3-hydroxy-2-phenylquinoline-4-carboxylic acid | CH...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetP-selectin glycoprotein ligand 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201927(3-hydroxy-2-phenylquinoline-4-carboxylic acid | CH...)
Affinity DataIC50: 6.00E+6nMAssay Description:Inhibition of P-selectin-mediated adhesion of HL60 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
LigandPNGBDBM50201927(3-hydroxy-2-phenylquinoline-4-carboxylic acid | CH...)
Affinity DataKd:  1.50E+4nMAssay Description:Binding affinity to human PDE10A catalytic domain expressed in Escherichia coli BL21-Gold(DE3) after 15 mins by SPR inhibition in solution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed