BDBM50201921 2-Biphenyl-4-yl-6-fluoro-3-hydroxy-quinoline-4-carboxylic acid::CHEMBL41719

SMILES OC(=O)c1c(O)c(nc2ccc(F)cc12)-c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=HVOMQBZOFIMPOL-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201921   

LigandPNGBDBM50201921(2-Biphenyl-4-yl-6-fluoro-3-hydroxy-quinoline-4-car...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
LigandPNGBDBM50201921(2-Biphenyl-4-yl-6-fluoro-3-hydroxy-quinoline-4-car...)
Affinity DataKi:  40nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article