BDBM50201840 4-[5-(4-chlorophenyl)-6-(4-dimethylaminophenylethynyl)pyrimidin-4-yl]piperazine-1-sulfonic acid dimethylamide::CHEMBL226505

SMILES CN(C)c1ccc(cc1)C#Cc1ncnc(N2CCN(CC2)S(=O)(=O)N(C)C)c1-c1ccc(Cl)cc1

InChI Key InChIKey=UBRMTBFFLCTZRW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201840   

TargetAdenosine kinase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201840(4-[5-(4-chlorophenyl)-6-(4-dimethylaminophenylethy...)
Affinity DataIC50: 13nMAssay Description:Inhibition of cytosolic adenosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine kinase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201840(4-[5-(4-chlorophenyl)-6-(4-dimethylaminophenylethy...)
Affinity DataIC50: 330nMAssay Description:Inhibition of adenosine kinase in intact cells assessed as adenosine phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed