BDBM50201828 CHEMBL226503::[5-(4-chlorophenyl)-6-(4-dimethylaminophenylethynyl)pyrimidin-4-yl]-[2-(1H-indol-3-yl)ethyl]amine

SMILES CN(C)c1ccc(cc1)C#Cc1ncnc(NCCc2c[nH]c3ccccc23)c1-c1ccc(Cl)cc1

InChI Key InChIKey=SQEKKPLUIMZWKA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201828   

TargetAdenosine kinase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201828([5-(4-chlorophenyl)-6-(4-dimethylaminophenylethyny...)
Affinity DataIC50: 38nMAssay Description:Inhibition of cytosolic adenosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine kinase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201828([5-(4-chlorophenyl)-6-(4-dimethylaminophenylethyny...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of adenosine kinase in intact cells assessed as adenosine phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed