BDBM50201826 6-(6-morpholin-4-ylpyridin-3-ylethynyl)-5-thiophen-3-ylpyrimidin-4-ylamine::CHEMBL226428

SMILES Nc1ncnc(C#Cc2ccc(nc2)N2CCOCC2)c1-c1ccsc1

InChI Key InChIKey=MITVCDGIMGCQME-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201826   

TargetAdenosine kinase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201826(6-(6-morpholin-4-ylpyridin-3-ylethynyl)-5-thiophen...)
Affinity DataIC50: 38nMAssay Description:Inhibition of cytosolic adenosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine kinase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201826(6-(6-morpholin-4-ylpyridin-3-ylethynyl)-5-thiophen...)
Affinity DataIC50: 212nMAssay Description:Inhibition of adenosine kinase in intact cells assessed as adenosine phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed