BDBM50201801 CHEMBL3942806

SMILES CCOC(=O)c1c(C)[nH]c(\C=C2/S\C(=N/c3ccc(F)cc3)N(C2=O)c2ccc(F)cc2)c1C

InChI Key InChIKey=SHFVCZWLBDNTHN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201801   

TargetM-phase inducer phosphatase 2(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50201801(CHEMBL3942806)
Affinity DataIC50: 2.87E+6nMAssay Description:Inhibition of human recombinant GST-tagged CDC25B assessed as reduction in dephosphorylation of florigenic phosphatase substrate preincubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50201801(CHEMBL3942806)
Affinity DataIC50: 6.09E+6nMAssay Description:Inhibition of human recombinant GST-tagged PTP1B catalytic domain expressed in Escherichia coli BL21-Conden plus (DE3) using pNPP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed