BDBM50201736 CHEMBL1962390

SMILES CC(C)C1=C(O)C(=O)\C(=C/NCC(O)=O)c2c(O)c(c(C)cc12)-c1c(C)cc2C(C(C)C)=C(O)C(=O)\C(=C/NCC(O)=O)c2c1O

InChI Key InChIKey=GVFGFAZBZIUXBQ-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50201736   

TargetApoptosis regulator Bcl-2(Human)
Wuhan University School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50201736(CHEMBL1962390)
Affinity DataIC50: 573nMAssay Description:Inhibition of FAM-Bid binding to human BCL2 expressed in Escherichia coli BL21 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Wuhan University School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50201736(CHEMBL1962390)
Affinity DataIC50: 521nMAssay Description:Inhibition of FAM-Bid binding to human MCL1 expressed in Escherichia coli BL21 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Wuhan University School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50201736(CHEMBL1962390)
Affinity DataKi:  121nMAssay Description:Inhibition of FAM-Bid binding to human MCL1 expressed in Escherichia coli BL21 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Wuhan University School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50201736(CHEMBL1962390)
Affinity DataKi:  224nMAssay Description:Inhibition of FAM-Bid binding to human BCL2 expressed in Escherichia coli BL21 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed