BDBM50201734 CHEMBL3951720

SMILES CC(C)C1=C(O)C(=O)\C(=C/NCCCC(O)=O)c2c(O)c(c(C)cc12)-c1c(C)cc2C(C(C)C)=C(O)C(=O)\C(=C/NCCCC(O)=O)c2c1O

InChI Key InChIKey=FFXRYZVMILEXAM-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50201734   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Wuhan University School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50201734(CHEMBL3951720)
Affinity DataIC50: 661nMAssay Description:Inhibition of FAM-Bid binding to human MCL1 expressed in Escherichia coli BL21 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Wuhan University School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50201734(CHEMBL3951720)
Affinity DataIC50: 596nMAssay Description:Inhibition of FAM-Bid binding to human BCL2 expressed in Escherichia coli BL21 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Wuhan University School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50201734(CHEMBL3951720)
Affinity DataKi:  94nMAssay Description:Inhibition of FAM-Bid binding to human MCL1 expressed in Escherichia coli BL21 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Wuhan University School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50201734(CHEMBL3951720)
Affinity DataKi:  235nMAssay Description:Inhibition of FAM-Bid binding to human BCL2 expressed in Escherichia coli BL21 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed