BDBM50201670 CHEMBL3930086

SMILES CC#C[C@@H](CC([O-])=O)c1ccc(OCc2cccc(CN(Cc3ccsc3)C(C)C)c2)cc1

InChI Key InChIKey=SMSIQLAGVMCTRR-UHFFFAOYSA-M

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201670   

TargetMelanocortin receptor 4(Rat)
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50201670(CHEMBL3930086)
Affinity DataEC50:  2.00E+4nMAssay Description:Agonist activity at GPR40 in rat RINm cells assessed as increase glucose-stimulated insulin secretion after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50201670(CHEMBL3930086)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human GPR40 expressed in HEK293 cells assessed as induction of intracellular Ca2+ flux preincubated for 40 mins measured for 180 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50201670(CHEMBL3930086)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human GPR40 expressed in HEK293 cells assessed as induction of IP1 formation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed