BDBM50201665 (E)-1-(1-methyl-4-oxoimidazolidin-2-ylidene)-3-(pyridin-2-yl)urea::CHEMBL391401

SMILES Cn1cc(O)nc1NC(=O)Nc1ccccn1

InChI Key InChIKey=OLXISMRXRFSPJK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201665   

TargetMetabotropic glutamate receptor 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50201665((E)-1-(1-methyl-4-oxoimidazolidin-2-ylidene)-3-(py...)
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at mGluR5 by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50201665((E)-1-(1-methyl-4-oxoimidazolidin-2-ylidene)-3-(py...)
Affinity DataIC50: 587nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed