BDBM50201572 CHEMBL3965469

SMILES Cc1nccn1-c1ccc(cn1)-c1cn(CC(=O)Nc2cccc(Cl)c2Cl)nn1

InChI Key InChIKey=FEYQJDCJMVTWIG-UHFFFAOYSA-N

Data  5 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50201572   

LigandPNGBDBM50201572(CHEMBL3965469)
Affinity DataEC50:  24nMAssay Description:Agonist activity at human GPR142 expressed in CHO cells measured after 30 to 60 mins by IP-One assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMed
LigandPNGBDBM50201572(CHEMBL3965469)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Cav1.2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMed
LigandPNGBDBM50201572(CHEMBL3965469)
Affinity DataEC50:  8nMAssay Description:Agonist activity at mouse GPR142 expressed in CHO cells measured for 3 to 5 mins by Fluo-4AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMed
LigandPNGBDBM50201572(CHEMBL3965469)
Affinity DataEC50:  24nMAssay Description:Agonist activity at human GPR142 expressed in CHO cells measured for 3 to 5 mins by Fluo-4AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50201572(CHEMBL3965469)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMed
LigandPNGBDBM50201572(CHEMBL3965469)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Nav1.5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMed
LigandPNGBDBM50201572(CHEMBL3965469)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMed
LigandPNGBDBM50201572(CHEMBL3965469)
Affinity DataEC50:  2nMAssay Description:Agonist activity at mouse GPR142 expressed in CHO cells measured after 30 to 60 mins by IP-One assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50201572(CHEMBL3965469)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMed