BDBM50201504 CHEMBL233555::N-(2-(dimethylamino)ethyl)-2-(3H-imidazo[4,5-c]pyridin-3-yl)-7-methyl-4-((S)-1-phenylethylamino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide

SMILES C[C@H](Nc1nc(nc2n(C)c(cc12)C(=O)NCCN(C)C)-n1cnc2ccncc12)c1ccccc1

InChI Key InChIKey=PIVJMAKIXQYHOB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201504   

TargetTyrosine-protein kinase JAK3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201504(N-(2-(dimethylamino)ethyl)-2-(3H-imidazo[4,5-c]pyr...)
Affinity DataIC50: 34nMAssay Description:Inhibition of JAK3 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201504(N-(2-(dimethylamino)ethyl)-2-(3H-imidazo[4,5-c]pyr...)
Affinity DataIC50: 19nMAssay Description:Inhibition of JAK2 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed