BDBM50201395 CHEMBL238719::N-(4-tert-butylphenyl)-3-methyl-5-(pyridin-4-ylmethylamino)isoxazole-4-carboxamide

SMILES Cc1noc(NCc2ccncc2)c1C(=O)Nc1ccc(cc1)C(C)(C)C

InChI Key InChIKey=YCJDQCDOTIDSLP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201395   

TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201395(N-(4-tert-butylphenyl)-3-methyl-5-(pyridin-4-ylmet...)
Affinity DataIC50: 420nMAssay Description:Inhibition of VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201395(N-(4-tert-butylphenyl)-3-methyl-5-(pyridin-4-ylmet...)
Affinity DataIC50: 280nMAssay Description:Inhibition of VEGFR1 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201395(N-(4-tert-butylphenyl)-3-methyl-5-(pyridin-4-ylmet...)
Affinity DataIC50: 210nMAssay Description:Inhibition of VEGFR2 by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed