BDBM50201364 3-methyl-5-(pyridin-4-ylmethylamino)-N-(4-(trifluoromethyl)phenyl)isoxazole-4-carboxamide::CHEMBL392513

SMILES Cc1noc(NCc2ccncc2)c1C(=O)Nc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=WJZJOYFICBHWRB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201364   

TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201364(3-methyl-5-(pyridin-4-ylmethylamino)-N-(4-(trifluo...)
Affinity DataIC50: 180nMAssay Description:Inhibition of VEGFR2 by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201364(3-methyl-5-(pyridin-4-ylmethylamino)-N-(4-(trifluo...)
Affinity DataIC50: 370nMAssay Description:Inhibition of VEGFR1 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201364(3-methyl-5-(pyridin-4-ylmethylamino)-N-(4-(trifluo...)
Affinity DataIC50: 560nMAssay Description:Inhibition of VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed