BDBM50201358 CHEMBL391127::N-(3,4-dichlorophenyl)-1-methyl-4-(pyridin-4-ylmethylamino)-1H-pyrazole-5-carboxamide

SMILES Cn1ncc(NCc2ccncc2)c1C(=O)Nc1ccc(Cl)c(Cl)c1

InChI Key InChIKey=SQWAVDLFFUTGHT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201358   

TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201358(N-(3,4-dichlorophenyl)-1-methyl-4-(pyridin-4-ylmet...)
Affinity DataIC50: 360nMAssay Description:Inhibition of VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201358(N-(3,4-dichlorophenyl)-1-methyl-4-(pyridin-4-ylmet...)
Affinity DataIC50: 82nMAssay Description:Inhibition of VEGFR2 by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201358(N-(3,4-dichlorophenyl)-1-methyl-4-(pyridin-4-ylmet...)
Affinity DataIC50: 250nMAssay Description:Inhibition of VEGFR1 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed