BDBM50201348 CHEMBL238530::N-(3,4-bis(trifluoromethyl)phenyl)-1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazole-5-carboxamide

SMILES Cn1cnc(NCc2ccncc2)c1C(=O)Nc1ccc(c(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=IVVUEJITPKKCOQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201348   

TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201348(N-(3,4-bis(trifluoromethyl)phenyl)-1-methyl-4-(pyr...)
Affinity DataIC50: 690nMAssay Description:Inhibition of VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201348(N-(3,4-bis(trifluoromethyl)phenyl)-1-methyl-4-(pyr...)
Affinity DataIC50: 580nMAssay Description:Inhibition of VEGFR1 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201348(N-(3,4-bis(trifluoromethyl)phenyl)-1-methyl-4-(pyr...)
Affinity DataIC50: 110nMAssay Description:Inhibition of VEGFR2 by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed