BDBM50201346 CHEMBL241084::N-(3,4-dimethoxyphenyl)-1-methyl-4-(pyridin-4-ylmethylamino)-1H-pyrazole-5-carboxamide

SMILES COc1ccc(NC(=O)c2c(NCc3ccncc3)cnn2C)cc1OC

InChI Key InChIKey=TXLNOFRGNOWXJK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201346   

TargetVascular endothelial growth factor receptor 1(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201346(N-(3,4-dimethoxyphenyl)-1-methyl-4-(pyridin-4-ylme...)
Affinity DataIC50: 350nMAssay Description:Inhibition of VEGFR1 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201346(N-(3,4-dimethoxyphenyl)-1-methyl-4-(pyridin-4-ylme...)
Affinity DataIC50: 91nMAssay Description:Inhibition of VEGFR2 by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201346(N-(3,4-dimethoxyphenyl)-1-methyl-4-(pyridin-4-ylme...)
Affinity DataIC50: 510nMAssay Description:Inhibition of VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed