BDBM50201310 1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(3-ethylphenyl)urea::CHEMBL231109

SMILES CCc1cccc(NC(=O)Nc2ccc(cc2)-c2csc3ccnc(N)c23)c1

InChI Key InChIKey=VCBUOQYGDSWJSM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201310   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201310(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...)
Affinity DataIC50: 25nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201310(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human KDR phosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed