BDBM50201255 CHEMBL429107::N-((R)-7-isobutyryl-2,4-dioxo-1,3,7-triaza-spiro[4.4]non-9-yl)-4-(2-methyl-quinolin-4-ylmethoxy)-benzamide

SMILES CC(C)C(=O)N1C[C@@H](NC(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C2(C1)NC(=O)NC2=O

InChI Key InChIKey=ATCZHZRQAQJGGH-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201255   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201255(N-((R)-7-isobutyryl-2,4-dioxo-1,3,7-triaza-spiro[4...)
Affinity DataIC50: 24nMAssay Description:Inhibition of porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201255(N-((R)-7-isobutyryl-2,4-dioxo-1,3,7-triaza-spiro[4...)
Affinity DataKi: >3.33E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201255(N-((R)-7-isobutyryl-2,4-dioxo-1,3,7-triaza-spiro[4...)
Affinity DataKi: >5.03E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed