BDBM50201246 CHEMBL442421::N-(1-(2,5-dioxoimidazolidin-4-yl)ethyl)-4-((2-methylquinolin-4-yl)methoxy)benzamide

SMILES CC(NC(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)c1[nH]c(=O)[nH]c1O

InChI Key InChIKey=BEHVPLNNVRKJAC-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50201246   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201246(N-(1-(2,5-dioxoimidazolidin-4-yl)ethyl)-4-((2-meth...)
Affinity DataIC50: 28nMAssay Description:Inhibition of porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201246(N-(1-(2,5-dioxoimidazolidin-4-yl)ethyl)-4-((2-meth...)
Affinity DataKi: >2.13E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201246(N-(1-(2,5-dioxoimidazolidin-4-yl)ethyl)-4-((2-meth...)
Affinity DataKi: >3.33E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201246(N-(1-(2,5-dioxoimidazolidin-4-yl)ethyl)-4-((2-meth...)
Affinity DataKi: >4.95E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201246(N-(1-(2,5-dioxoimidazolidin-4-yl)ethyl)-4-((2-meth...)
Affinity DataKi: >5.03E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed