BDBM50201236 4-(2,4-dichlorophenylamino)-6-methoxy-7-(4-(4-methylpiperazin-1-yl)but-1-ynyl)quinoline-3-carbonitrile::CHEMBL240829

SMILES COc1cc2c(Nc3ccc(Cl)cc3Cl)c(cnc2cc1C#CCCN1CCN(C)CC1)C#N

InChI Key InChIKey=GAPDGBDSBXIFHK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201236   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201236(4-(2,4-dichlorophenylamino)-6-methoxy-7-(4-(4-meth...)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of Src activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201236(4-(2,4-dichlorophenylamino)-6-methoxy-7-(4-(4-meth...)
Affinity DataIC50: 430nMAssay Description:Inhibition of Src in rat fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed