BDBM50201225 (R)-3-(2,5-dioxoimidazolidin-4-yl)-N-(4-((2-methylquinolin-4-yl)methoxy)phenyl)propanamide::CHEMBL393863

SMILES Cc1cc(COc2ccc(NC(=O)CCc3[nH]c(=O)[nH]c3O)cc2)c2ccccc2n1

InChI Key InChIKey=PTPSJTBFHYFECV-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50201225   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201225((R)-3-(2,5-dioxoimidazolidin-4-yl)-N-(4-((2-methyl...)
Affinity DataIC50: 150nMAssay Description:Inhibition of porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201225((R)-3-(2,5-dioxoimidazolidin-4-yl)-N-(4-((2-methyl...)
Affinity DataIC50: 150nMAssay Description:Inhibition of porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201225((R)-3-(2,5-dioxoimidazolidin-4-yl)-N-(4-((2-methyl...)
Affinity DataKi: >2.13E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201225((R)-3-(2,5-dioxoimidazolidin-4-yl)-N-(4-((2-methyl...)
Affinity DataKi: >3.33E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201225((R)-3-(2,5-dioxoimidazolidin-4-yl)-N-(4-((2-methyl...)
Affinity DataKi: >4.95E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201225((R)-3-(2,5-dioxoimidazolidin-4-yl)-N-(4-((2-methyl...)
Affinity DataKi: >5.03E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed