BDBM50201050 (1R,6S)-2-bromo-5-(3,8-diaza-bicyclo[4.2.0]oct-8-yl)-nicotinamide::5-((1R,6S)-3,8-diaza-bicyclo[4.2.0]octan-8-yl)-2-bromonicotinamide::CHEMBL376273

SMILES NC(=O)c1cc(cnc1Br)N1C[C@@H]2CCNC[C@H]12

InChI Key InChIKey=USBWZALTSNTXBS-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201050   

TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Burnham Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50201050((1R,6S)-2-bromo-5-(3,8-diaza-bicyclo[4.2.0]oct-8-y...)
Affinity DataEC50:  2.34E+4nMAssay Description:Agonist activity against human alpha3beta4 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201050((1R,6S)-2-bromo-5-(3,8-diaza-bicyclo[4.2.0]oct-8-y...)
Affinity DataEC50:  1.49E+3nMAssay Description:Agonist activity at human alpha4beta2 ACHR expressed in HEK293 cells assessed as change in intracellular calcium concentration by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Burnham Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50201050((1R,6S)-2-bromo-5-(3,8-diaza-bicyclo[4.2.0]oct-8-y...)
Affinity DataEC50:  1.48E+3nMAssay Description:Agonist activity against human alpha4beta2 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed