BDBM50200986 CHEMBL3902955::US10138212, Example 48

SMILES COc1cccc2c(nc(N)nc12)C(=O)NCc1cccc(COC2CCCC2)n1

InChI Key InChIKey=DMMOMDAFEVHKEJ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50200986   

TargetAdenosine receptor A2a(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50200986(CHEMBL3902955 | US10138212, Example 48)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]5-amino-7-[2- phenethyl]-2-(furan-2-yl)-7H-pyrazolo[4,3-e][l,2,4]triazolo[l,5-c]pyrimidine from human adenosine A2A receptor expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2018
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50200986(CHEMBL3902955 | US10138212, Example 48)
Affinity DataKi:  0.5nMAssay Description:Binding affinities of compounds of the invention for the human A2a receptor were determined in a competition binding assay using Scintillation Proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent