BDBM50200985 CHEMBL3965187::US10138212, Example 107

SMILES [2H]C([2H])(NC(=O)c1nc(N)nc2c(OC)cccc12)c1cccc(n1)C([2H])([2H])c1cncc(OCCOC)c1

InChI Key InChIKey=BVKYBOZVLITWKN-WDVOAUESSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50200985   

TargetAdenosine receptor A2a(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50200985(CHEMBL3965187 | US10138212, Example 107)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]5-amino-7-[2- phenethyl]-2-(furan-2-yl)-7H-pyrazolo[4,3-e][l,2,4]triazolo[l,5-c]pyrimidine from human adenosine A2A receptor expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2018
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50200985(CHEMBL3965187 | US10138212, Example 107)
Affinity DataKi:  2nMAssay Description:Binding affinities of compounds of the invention for the human A2a receptor were determined in a competition binding assay using Scintillation Proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent