BDBM50200966 CHEMBL220296::ethyl2-amino-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate

SMILES CCOC(=O)C(C#N)C1C(C(=O)OCC)C(=N)Oc2ccccc12

InChI Key InChIKey=KJGRHZCOMOPYTQ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50200966   

TargetBcl-2-like protein 2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200966(ethyl2-amino-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-ch...)
Affinity DataKi:  6.97E+5nMAssay Description:Binding affinity to Bclw by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200966(ethyl2-amino-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-ch...)
Affinity DataKi:  5.70E+5nMAssay Description:Binding affinity to BclXL by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200966(ethyl2-amino-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-ch...)
Affinity DataKi:  5.31E+5nMAssay Description:Binding affinity to Bcl2 by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed