BDBM50200592 (+)-2-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methyl-pentyl]-piperidin-4-yl}-2-oxo-2,3-dihydro-benzimidazol-1-yl)-N-methyl-acetamide::(+/-)-2-(3-(1-(3-(5-methoxy-2-methylphenoxy)-4-methylpentyl)piperidin-4-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-methylacetamide::(-)-2-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methyl-pentyl]-piperidin-4-yl}-2-oxo-2,3-dihydro-benzimidazol-1-yl)-N-methyl-acetamide::2-(3-(1-(3-(5-methoxy-2-methylphenoxy)-4-methylpentyl)piperidin-4-yl)-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)-N-methylacetamide::2-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methyl-pentyl]-piperidin-4-yl}-2-oxo-2,3-dihydro-benzimidazol-1-yl)-N-methyl-acetamide::CHEMBL391487

SMILES CNC(=O)Cn1c2ccccc2n(C2CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)c1=O

InChI Key InChIKey=OUDYUUVZVNMOPP-UHFFFAOYSA-N

Data  9 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50200592   

TargetNociceptin receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200592((-)-2-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-meth...)
Affinity DataIC50: 712nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200592((-)-2-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-meth...)
Affinity DataIC50: 712nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200592((-)-2-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-meth...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200592((-)-2-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-meth...)
Affinity DataKi:  56nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200592((-)-2-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-meth...)
Affinity DataKi:  101nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200592((-)-2-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-meth...)
Affinity DataKi:  166nMAssay Description:Displacement of [3H]Diprenorphine from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200592((-)-2-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-meth...)
Affinity DataKi:  449nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200592((-)-2-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-meth...)
Affinity DataKi:  449nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200592((-)-2-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-meth...)
Affinity DataKi:  534nMAssay Description:Displacement of [3H]U-69593 from KOP receptor in guinea pig cortical tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200592((-)-2-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-meth...)
Affinity DataKi:  534nMAssay Description:Displacement of [3H]U-69593 from KOP receptor in guinea pig cortical tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200592((-)-2-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-meth...)
Affinity DataKi:  4.53E+3nMAssay Description:Displacement of [3H]naltrindole from human DOP receptor expressed in deltaC6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed