BDBM50200394 CHEMBL387187::Cyclopropanecarboxylic acid (3-(6-(3-trifluoromethyl-phenylamino)-pyrimidin-4-ylamino)-phenyl)-amide::N-3-6-3-trifluoromethyl)phenylamino)pyrimidin-4-ylamino)phenyl)cyclopropanecarboxamide

SMILES c1cc(cc(c1)Nc2cc(ncn2)Nc3cccc(c3)NC(=O)C4CC4)C(F)(F)F

InChI Key InChIKey=YOHYSYJDKVYCJI-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50200394   

TargetEpidermal growth factor receptor(Human)
Activesight

Curated by ChEMBL
LigandPNGBDBM50200394(Cyclopropanecarboxylic acid (3-(6-(3-trifluorometh...)
Affinity DataIC50: 21nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Activesight

Curated by ChEMBL
LigandPNGBDBM50200394(Cyclopropanecarboxylic acid (3-(6-(3-trifluorometh...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora-AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Activesight

Curated by ChEMBL
LigandPNGBDBM50200394(Cyclopropanecarboxylic acid (3-(6-(3-trifluorometh...)
Affinity DataIC50: 21nMAssay Description:Inhibition of wild type EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50200394(Cyclopropanecarboxylic acid (3-(6-(3-trifluorometh...)
Affinity DataIC50: 7.64E+3nMAssay Description:Inhibition of erbB4/Her4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed