BDBM50200340 (+/-)-huprine Y-HCl::(+/-)-huprineY hydrochloride::CHEMBL536047

SMILES CC1=CC2CC(C1)c1c(C2)nc2cc(Cl)ccc2c1N

InChI Key

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50200340   

TargetCholinesterase(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50200340((+/-)-huprineY hydrochloride | (+/-)-huprine Y-HCl...)
Affinity DataIC50: 236nMAssay Description:Inhibition of human serum BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50200340((+/-)-huprineY hydrochloride | (+/-)-huprine Y-HCl...)
Affinity DataIC50: 0.780nMAssay Description:Inhibition of human erythrocyte AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50200340((+/-)-huprineY hydrochloride | (+/-)-huprine Y-HCl...)
Affinity DataIC50: 4.23nMAssay Description:Inhibition of bovine erythrocyte AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50200340((+/-)-huprineY hydrochloride | (+/-)-huprine Y-HCl...)
Affinity DataIC50: 0.690nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins prior substrate addition measured after 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCholinesterase(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50200340((+/-)-huprineY hydrochloride | (+/-)-huprine Y-HCl...)
Affinity DataIC50: 175nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins prior substrate addition measured after 5 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50200340((+/-)-huprineY hydrochloride | (+/-)-huprine Y-HCl...)
Affinity DataKi:  0.0330nMAssay Description:Binding affinity to human AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed