BDBM50200111 CHEMBL3981566

SMILES CC(=O)Nc1ccc(cc1)-n1cc(nn1)-c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=VNFSDDHWIVSKFW-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50200111   

TargetPolypeptide N-acetylgalactosaminyltransferase 2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200111(CHEMBL3981566)
Affinity DataIC50: 4.30E+5nMAssay Description:Inhibition of ppGalNAcT2 (unknown origin) in presence of OGT, EA2 and UDP-GlcNAc incubated for 25 mins at 37 degCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2018
Entry Details Article
PubMed
TargetUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200111(CHEMBL3981566)
Affinity DataIC50: 1.39E+5nMAssay Description:Inhibition of OGT (unknown origin) assessed as reduction in GlcNAc transfer to CKII peptide incubated for 60 mins by HPLC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2018
Entry Details Article
PubMed
TargetUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200111(CHEMBL3981566)
Affinity DataKi:  9.20E+4nMAssay Description:Noncompetitive inhibition of OGT (unknown origin) using variable UDP-GlcNAc levels and fixed CKII peptide level by UDP-Glo glycosyltransferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2018
Entry Details Article
PubMed
TargetUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200111(CHEMBL3981566)
Affinity DataKi:  3.10E+5nMAssay Description:Noncompetitive inhibition of OGT (unknown origin) using fixed UDP-GlcNAc levels and variable CKII peptide level by UDP-Glo glycosyltransferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2018
Entry Details Article
PubMed