BDBM50200045 2-(4-phenylpiperidin-1-yl)-N-(m-tolyl)acetamide::CHEMBL216393
SMILES Cc1cccc(NC(=O)CN2CCC(CC2)c2ccccc2)c1
InChI Key InChIKey=ZMEYWYCGMCZGRN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50200045
Affinity DataEC50: 170nMAssay Description:Agonist activity at human D4.4 receptor in HEK293 cells coexpressing G-alpha-qo5 by FLIPRMore data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:Agonist activity at human D4 receptor expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human D4 receptor expressed in CHOK1 cells assessed as suppression of dopamine-induced inhibition of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at human D3 receptor expressed in CHOK1 cells assessed as inhibition of dopamine-induced beta-arrestin recruitment measured after...More data for this Ligand-Target Pair
Affinity DataEC50: 242nMAssay Description:Agonist activity at human D4 receptor expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by luminesce...More data for this Ligand-Target Pair
Affinity DataIC50: 135nMAssay Description:Antagonist activity at human D4 receptor expressed in CHOK1 cells assessed as inhibition of dopamine-induced beta-arrestin recruitment measured after...More data for this Ligand-Target Pair
Affinity DataIC50: 1.64E+4nMAssay Description:Antagonist activity at human D2L receptor expressed in CHOK1 cells assessed as suppression of dopamine-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
Affinity DataIC50: 7.69E+3nMAssay Description:Antagonist activity at human D2L receptor expressed in CHOK1 cells assessed as inhibition of dopamine-induced beta-arrestin recruitment measured afte...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H](R)-(+)-7-OH-DPAT from human D4.4 receptor expressed in HEK293 cell membranes measured after 90 mins by scintillation counting me...More data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Displacement of [3H]N-methylspiperone from human D4.4 receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting me...More data for this Ligand-Target Pair
Affinity DataKi: 127nMAssay Description:Displacement of [3H](R)-(+)-7-OH-DPAT from human D2L receptor expressed in HEK293 cell membranes measured after 90 mins by scintillation counting met...More data for this Ligand-Target Pair
Affinity DataKi: 433nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting meth...More data for this Ligand-Target Pair
Affinity DataKi: 777nMAssay Description:Displacement of [3H](R)-(+)-7-OH-DPAT from human D3 receptor expressed in HEK293 cell membranes measured after 90 mins by scintillation counting meth...More data for this Ligand-Target Pair
Affinity DataKi: 821nMAssay Description:Displacement of [3H]N-methylspiperone from human D2L receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting met...More data for this Ligand-Target Pair