BDBM50200043 3-methyl-N-(3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzamide::CHEMBL216794

SMILES Cc1cccc(c1)C(=O)NCN1CCC(CC1)c1ccccn1

InChI Key InChIKey=MJWBNONYVUDZCQ-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50200043   

TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200043(3-methyl-N-(3',4',5',6'-tetrahydro-2'H-[2,4'-bipyr...)
Affinity DataEC50:  9nMAssay Description:Agonist activity at human D4.4 receptor in HEK293 cells coexpressing G-alpha-qo5 by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200043(3-methyl-N-(3',4',5',6'-tetrahydro-2'H-[2,4'-bipyr...)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]spiperone from human D4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200043(3-methyl-N-(3',4',5',6'-tetrahydro-2'H-[2,4'-bipyr...)
Affinity DataKi:  3.50E+3nMAssay Description:Agonist activity at human D2 receptor in HEK293 cells coexpressing G-alpha-qo5 by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200043(3-methyl-N-(3',4',5',6'-tetrahydro-2'H-[2,4'-bipyr...)
Affinity DataKi:  3.50E+3nMAssay Description:Displacement of [125I]7-OH-PIPAT from human D2L receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed