BDBM50200041 CHEMBL219261::N-(2-methyl-4-fluorophenyl)-2-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-yl)acetamide

SMILES Cc1cc(F)ccc1NC(=O)CN1CCC(CC1)c1cccc[n+]1[O-]

InChI Key InChIKey=MYDLUAXWIJFAIL-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50200041   

TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200041(N-(2-methyl-4-fluorophenyl)-2-(1-oxy-3',4',5',6'-t...)
Affinity DataEC50:  60nMAssay Description:Agonist activity at human D4.4 receptor in HEK293 cells coexpressing G-alpha-qo5 by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200041(N-(2-methyl-4-fluorophenyl)-2-(1-oxy-3',4',5',6'-t...)
Affinity DataEC50:  100nMAssay Description:Agonist activity at rat D4 receptor in HEK293 cells coexpressing G-alpha-qo5 by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200041(N-(2-methyl-4-fluorophenyl)-2-(1-oxy-3',4',5',6'-t...)
Affinity DataKi:  405nMAssay Description:Displacement of [3H]A369508 from human D4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200041(N-(2-methyl-4-fluorophenyl)-2-(1-oxy-3',4',5',6'-t...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human D2S receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200041(N-(2-methyl-4-fluorophenyl)-2-(1-oxy-3',4',5',6'-t...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]7-OH-PIPAT from human D2L receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed