BDBM50199893 3-((1R,2R,9-alpha-S)-1,2-dimethyl-octahydro-1H-quinolizin-2-yl)phenol::CHEMBL219012

SMILES C[C@H]1[C@@H]2CCCCN2CC[C@@]1(C)c1cccc(O)c1

InChI Key InChIKey=QSNKCELEYRXWPD-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50199893   

TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50199893(3-((1R,2R,9-alpha-S)-1,2-dimethyl-octahydro-1H-qui...)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity against human cloned mu opioid receptor expressed in CHO cells assessed as inhibition of loperamide-stimulated [35S]GTP-gamma-S b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50199893(3-((1R,2R,9-alpha-S)-1,2-dimethyl-octahydro-1H-qui...)
Affinity DataKi:  69nMAssay Description:Partial agonist activity at human cloned kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50199893(3-((1R,2R,9-alpha-S)-1,2-dimethyl-octahydro-1H-qui...)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50199893(3-((1R,2R,9-alpha-S)-1,2-dimethyl-octahydro-1H-qui...)
Affinity DataKi:  220nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed